{"id":110153,"date":"2026-07-22T15:54:02","date_gmt":"2026-07-22T13:54:02","guid":{"rendered":"https:\/\/rd-biotech.tetedecom.pro\/?page_id=110153"},"modified":"2026-07-27T16:10:22","modified_gmt":"2026-07-27T14:10:22","slug":"recombinant-protein-biomanufacturing","status":"publish","type":"page","link":"https:\/\/rd-biotech.tetedecom.pro\/en\/recombinant-protein-expression\/recombinant-protein-biomanufacturing\/","title":{"rendered":"Recombinant protein biomanufacturing"},"content":{"rendered":"<div class=\"wpb-content-wrapper\"><p>[vc_row row_height_percent=&#8221;40&#8243; back_image=&#8221;109703&#8243; back_repeat=&#8221;no-repeat&#8221; back_position=&#8221;center center&#8221; overlay_color=&#8221;color-xsdn&#8221; overlay_alpha=&#8221;70&#8243; gutter_size=&#8221;3&#8243; column_width_percent=&#8221;100&#8243; shift_y=&#8221;0&#8243; z_index=&#8221;0&#8243; content_parallax=&#8221;0&#8243; uncode_shortcode_id=&#8221;662434&#8243; row_height_pixel=&#8221;400&#8243; overlay_color_type=&#8221;uncode-palette&#8221;][vc_column column_width_use_pixel=&#8221;yes&#8221; position_horizontal=&#8221;left&#8221; position_vertical=&#8221;middle&#8221; gutter_size=&#8221;1&#8243; overlay_alpha=&#8221;50&#8243; shift_x=&#8221;0&#8243; shift_y=&#8221;0&#8243; shift_y_down=&#8221;0&#8243; z_index=&#8221;0&#8243; medium_width=&#8221;0&#8243; align_mobile=&#8221;align_center_mobile&#8221; mobile_width=&#8221;0&#8243; width=&#8221;1\/1&#8243; uncode_shortcode_id=&#8221;484880&#8243;][uncode_breadcrumbs][vc_empty_space empty_h=&#8221;2&#8243;][vc_custom_heading auto_text=&#8221;yes&#8221; text_size=&#8221;fontsize-155944&#8243; text_weight=&#8221;200&#8243; text_space=&#8221;fontspace-781688&#8243; uncode_shortcode_id=&#8221;497824&#8243;][\/vc_custom_heading][vc_empty_space empty_h=&#8221;2&#8243;][vc_custom_heading text_size=&#8221;h5&#8243; text_weight=&#8221;200&#8243; css_animation=&#8221;alpha-anim&#8221; animation_speed=&#8221;2000&#8243; uncode_shortcode_id=&#8221;223390&#8243;]<\/p>\n<p class=\"PDq2pG_selectionAnchorContainer\" data-start=\"215\" data-end=\"368\">Accelerate your bioproduction projects with comprehensive support, from in silico analysis through to the large-scale production of recombinant proteins.<\/p>\n<p class=\"PDq2pG_selectionAnchorContainer\" data-start=\"215\" data-end=\"368\">Our customized solutions provide optimized yields, high quality and reliable processes tailored to research, preclinical and clinical applications.<\/p>\n<p>[\/vc_custom_heading][\/vc_column][\/vc_row][vc_row row_height_percent=&#8221;0&#8243; override_padding=&#8221;yes&#8221; h_padding=&#8221;2&#8243; top_padding=&#8221;3&#8243; bottom_padding=&#8221;0&#8243; back_color=&#8221;color-xsdn&#8221; overlay_color=&#8221;color-xsdn&#8221; overlay_alpha=&#8221;50&#8243; gutter_size=&#8221;3&#8243; column_width_percent=&#8221;100&#8243; shift_y=&#8221;0&#8243; z_index=&#8221;0&#8243; content_parallax=&#8221;0&#8243; uncode_shortcode_id=&#8221;174184&#8243; row_height_pixel=&#8221;0&#8243; overlay_color_type=&#8221;uncode-palette&#8221; back_color_type=&#8221;uncode-palette&#8221; el_id=&#8221;in-silico-feasibility-assessment-and-system-selection&#8221;][vc_column column_width_use_pixel=&#8221;yes&#8221; position_horizontal=&#8221;left&#8221; position_vertical=&#8221;middle&#8221; gutter_size=&#8221;3&#8243; overlay_alpha=&#8221;50&#8243; shift_x=&#8221;0&#8243; shift_y=&#8221;0&#8243; shift_y_down=&#8221;0&#8243; z_index=&#8221;0&#8243; medium_width=&#8221;0&#8243; align_mobile=&#8221;align_center_mobile&#8221; mobile_width=&#8221;0&#8243; width=&#8221;1\/1&#8243; uncode_shortcode_id=&#8221;932974&#8243;][vc_custom_heading text_color=&#8221;color-109923&#8243; text_size=&#8221;h1&#8243; text_weight=&#8221;400&#8243; uncode_shortcode_id=&#8221;504398&#8243; text_color_type=&#8221;uncode-palette&#8221; el_id=&#8221;avantages-systeme-hybridomes&#8221;]In silico feasibility assessment and system selection[\/vc_custom_heading][\/vc_column][\/vc_row][vc_row row_height_percent=&#8221;40&#8243; back_color=&#8221;color-xsdn&#8221; overlay_color=&#8221;color-xsdn&#8221; overlay_alpha=&#8221;70&#8243; gutter_size=&#8221;3&#8243; column_width_percent=&#8221;100&#8243; shift_y=&#8221;0&#8243; z_index=&#8221;0&#8243; content_parallax=&#8221;0&#8243; uncode_shortcode_id=&#8221;156057&#8243; row_height_pixel=&#8221;400&#8243; overlay_color_type=&#8221;uncode-palette&#8221; back_color_type=&#8221;uncode-palette&#8221;][vc_column column_width_use_pixel=&#8221;yes&#8221; position_horizontal=&#8221;left&#8221; position_vertical=&#8221;middle&#8221; gutter_size=&#8221;3&#8243; overlay_alpha=&#8221;50&#8243; shift_x=&#8221;0&#8243; shift_y=&#8221;0&#8243; shift_y_down=&#8221;0&#8243; z_index=&#8221;0&#8243; medium_width=&#8221;0&#8243; align_mobile=&#8221;align_center_mobile&#8221; mobile_width=&#8221;0&#8243; width=&#8221;1\/1&#8243; uncode_shortcode_id=&#8221;932974&#8243;][vc_row_inner row_inner_height_percent=&#8221;0&#8243; overlay_alpha=&#8221;50&#8243; gutter_size=&#8221;4&#8243; shift_y=&#8221;0&#8243; z_index=&#8221;0&#8243; uncode_shortcode_id=&#8221;102621&#8243;][vc_column_inner column_width_percent=&#8221;100&#8243; gutter_size=&#8221;3&#8243; expand_height=&#8221;yes&#8221; back_image=&#8221;88214&#8243; overlay_alpha=&#8221;50&#8243; radius=&#8221;hg&#8221; shift_x=&#8221;0&#8243; shift_y=&#8221;0&#8243; shift_y_down=&#8221;0&#8243; z_index=&#8221;0&#8243; medium_width=&#8221;0&#8243; mobile_width=&#8221;0&#8243; width=&#8221;5\/12&#8243; uncode_shortcode_id=&#8221;183860&#8243;][\/vc_column_inner][vc_column_inner width=&#8221;7\/12&#8243;][vc_column_text uncode_shortcode_id=&#8221;214479&#8243;]<\/p>\n<p class=\"PDq2pG_selectionAnchorContainer\" data-start=\"583\" data-end=\"692\">Before beginning r<strong>ecombinant protein production<\/strong>, we perform an in-depth in silico feasibility study covering:<\/p>\n<ul data-start=\"694\" data-end=\"783\">\n<li data-section-id=\"k5kith\" data-start=\"694\" data-end=\"713\">Sequence analysis<\/li>\n<li data-section-id=\"17drezs\" data-start=\"714\" data-end=\"736\">Structure prediction<\/li>\n<li data-section-id=\"tn9xnf\" data-start=\"737\" data-end=\"783\">Assessment of expression and stability risks<\/li>\n<\/ul>\n<p data-start=\"785\" data-end=\"1039\">This scientific assessment enables us to <strong>select the optimal recombinant protein expression system <\/strong>(<a href=\"\/approche-multisysteme\/\">CHO, HEK, <em data-start=\"893\" data-end=\"902\">E. coli<\/em>, yeast or cell-free<\/a>) according to your target protein and its intended application, whether for research, diagnostics or therapeutic use.<\/p>\n<p data-start=\"1041\" data-end=\"1125\"><strong data-start=\"1041\" data-end=\"1056\">The result:<\/strong> an informed decision, minimized risks and considerable time savings.<\/p>\n<h2 data-section-id=\"1nwr0we\" data-start=\"1127\" data-end=\"1178\"><\/h2>\n<p>[\/vc_column_text][\/vc_column_inner][\/vc_row_inner][\/vc_column][\/vc_row][vc_row row_height_percent=&#8221;0&#8243; override_padding=&#8221;yes&#8221; h_padding=&#8221;2&#8243; top_padding=&#8221;3&#8243; bottom_padding=&#8221;0&#8243; back_color=&#8221;color-xsdn&#8221; overlay_alpha=&#8221;50&#8243; gutter_size=&#8221;3&#8243; column_width_percent=&#8221;100&#8243; shift_y=&#8221;0&#8243; z_index=&#8221;0&#8243; content_parallax=&#8221;0&#8243; uncode_shortcode_id=&#8221;786819&#8243; back_color_type=&#8221;uncode-palette&#8221; el_id=&#8221;expression-plasmid-construction-and-optimization&#8221;][vc_column column_width_use_pixel=&#8221;yes&#8221; position_horizontal=&#8221;left&#8221; position_vertical=&#8221;middle&#8221; gutter_size=&#8221;3&#8243; overlay_alpha=&#8221;50&#8243; shift_x=&#8221;0&#8243; shift_y=&#8221;0&#8243; shift_y_down=&#8221;0&#8243; z_index=&#8221;0&#8243; medium_width=&#8221;0&#8243; align_mobile=&#8221;align_center_mobile&#8221; mobile_width=&#8221;0&#8243; width=&#8221;1\/1&#8243; uncode_shortcode_id=&#8221;932974&#8243;][vc_custom_heading text_color=&#8221;color-109923&#8243; text_size=&#8221;h1&#8243; text_weight=&#8221;400&#8243; uncode_shortcode_id=&#8221;212982&#8243; text_color_type=&#8221;uncode-palette&#8221;]Expression plasmid construction and optimization[\/vc_custom_heading][vc_column_text text_color=&#8221;color-109923&#8243; uncode_shortcode_id=&#8221;131557&#8243; text_color_type=&#8221;uncode-palette&#8221;]We provide <strong>optimized gene synthesis<\/strong> and design and construct your <strong>expression plasmid<\/strong>, incorporating codon optimization and regulatory elements suited to the selected system. The resulting plasmid is validated through quality-control testing.[\/vc_column_text][\/vc_column][\/vc_row][vc_row row_height_percent=&#8221;0&#8243; override_padding=&#8221;yes&#8221; h_padding=&#8221;2&#8243; top_padding=&#8221;2&#8243; bottom_padding=&#8221;3&#8243; back_color=&#8221;color-xsdn&#8221; overlay_alpha=&#8221;50&#8243; gutter_size=&#8221;3&#8243; column_width_percent=&#8221;100&#8243; shift_y=&#8221;0&#8243; z_index=&#8221;0&#8243; content_parallax=&#8221;0&#8243; uncode_shortcode_id=&#8221;628186&#8243; back_color_type=&#8221;uncode-palette&#8221;][vc_column column_width_use_pixel=&#8221;yes&#8221; position_horizontal=&#8221;left&#8221; position_vertical=&#8221;middle&#8221; gutter_size=&#8221;3&#8243; overlay_alpha=&#8221;50&#8243; shift_x=&#8221;0&#8243; shift_y=&#8221;0&#8243; shift_y_down=&#8221;0&#8243; z_index=&#8221;0&#8243; medium_width=&#8221;0&#8243; align_mobile=&#8221;align_center_mobile&#8221; mobile_width=&#8221;0&#8243; width=&#8221;1\/1&#8243; uncode_shortcode_id=&#8221;932974&#8243;][vc_tabs tab_scrolling=&#8221;yes&#8221; uncode_shortcode_id=&#8221;605913&#8243; el_class=&#8221;tab-services mobile-tabs-to-dropdown&#8221;][vc_tab gutter_size=&#8221;2&#8243; column_padding=&#8221;2&#8243; title=&#8221;Comprehensive support from cloning to recombinant protein expression&#8221; tab_id=&#8221;1777882602171-4-101784811151502&#8243;][vc_row_inner][vc_column_inner column_width_percent=&#8221;100&#8243; gutter_size=&#8221;3&#8243; expand_height=&#8221;yes&#8221; overlay_alpha=&#8221;50&#8243; shift_x=&#8221;0&#8243; shift_y=&#8221;0&#8243; shift_y_down=&#8221;0&#8243; z_index=&#8221;0&#8243; medium_width=&#8221;0&#8243; mobile_width=&#8221;0&#8243; width=&#8221;1\/2&#8243; uncode_shortcode_id=&#8221;186496&#8243; el_class=&#8221;service-box&#8221;][vc_column_text uncode_shortcode_id=&#8221;777661&#8243;]<\/p>\n<p class=\"PDq2pG_selectionAnchorContainer\" style=\"text-align: left;\" data-start=\"1624\" data-end=\"1750\">We manage the <strong>entire cloning and protein-expression process<\/strong>, from optimized gene synthesis through to final vector validation.<\/p>\n<p style=\"text-align: left;\" data-start=\"1752\" data-end=\"1892\">Our services include <strong>custom vector design<\/strong>, subcloning, screening and full sequencing to ensure the quality and conformity of each construct.<\/p>\n<p>[\/vc_column_text][\/vc_column_inner][vc_column_inner column_width_percent=&#8221;100&#8243; gutter_size=&#8221;3&#8243; expand_height=&#8221;yes&#8221; back_image=&#8221;99909&#8243; overlay_alpha=&#8221;50&#8243; radius=&#8221;xl&#8221; shift_x=&#8221;0&#8243; shift_y=&#8221;0&#8243; shift_y_down=&#8221;0&#8243; z_index=&#8221;0&#8243; medium_width=&#8221;0&#8243; mobile_width=&#8221;0&#8243; width=&#8221;1\/2&#8243; uncode_shortcode_id=&#8221;190947&#8243;][\/vc_column_inner][\/vc_row_inner][\/vc_tab][vc_tab gutter_size=&#8221;2&#8243; column_padding=&#8221;2&#8243; title=&#8221;Vector designs tailored to your needs&#8221; tab_id=&#8221;1772808992395-2-317775349915352921784811151502&#8243;][vc_row_inner row_inner_height_percent=&#8221;0&#8243; overlay_alpha=&#8221;50&#8243; gutter_size=&#8221;3&#8243; shift_y=&#8221;0&#8243; z_index=&#8221;0&#8243; uncode_shortcode_id=&#8221;256557&#8243; el_class=&#8221;services-hover vc_custom_preserve_mobile&#8221;][vc_column_inner column_width_percent=&#8221;100&#8243; gutter_size=&#8221;3&#8243; expand_height=&#8221;yes&#8221; overlay_alpha=&#8221;50&#8243; shift_x=&#8221;0&#8243; shift_y=&#8221;0&#8243; shift_y_down=&#8221;0&#8243; z_index=&#8221;0&#8243; medium_width=&#8221;0&#8243; mobile_width=&#8221;0&#8243; width=&#8221;1\/2&#8243; uncode_shortcode_id=&#8221;144551&#8243; el_class=&#8221;service-box&#8221;][vc_column_text uncode_shortcode_id=&#8221;171780&#8243;]<\/p>\n<p style=\"text-align: left;\">Every vector is specifically designed for the selected expression system to <strong>optimize protein expression<\/strong> yield, stability and quality.<\/p>\n<p>At this stage, we can incorporate a tag of your choice (or work without a tag) as well as an optional cleavage site to <strong>obtain a native recombinant protein following purificatio<\/strong>n.[\/vc_column_text][\/vc_column_inner][vc_column_inner column_width_percent=&#8221;100&#8243; gutter_size=&#8221;3&#8243; expand_height=&#8221;yes&#8221; back_image=&#8221;99674&#8243; overlay_alpha=&#8221;50&#8243; radius=&#8221;xl&#8221; shift_x=&#8221;0&#8243; shift_y=&#8221;0&#8243; shift_y_down=&#8221;0&#8243; z_index=&#8221;0&#8243; medium_width=&#8221;0&#8243; mobile_width=&#8221;0&#8243; width=&#8221;1\/2&#8243; uncode_shortcode_id=&#8221;192412&#8243;][\/vc_column_inner][\/vc_row_inner][\/vc_tab][vc_tab gutter_size=&#8221;2&#8243; column_padding=&#8221;2&#8243; title=&#8221;Customized solutions and rigorous quality control&#8221; tab_id=&#8221;1757666499-2-8617775349915356871784811151502&#8243;][vc_row_inner row_inner_height_percent=&#8221;0&#8243; overlay_alpha=&#8221;50&#8243; gutter_size=&#8221;3&#8243; shift_y=&#8221;0&#8243; z_index=&#8221;0&#8243; uncode_shortcode_id=&#8221;256557&#8243; el_class=&#8221;services-hover vc_custom_preserve_mobile&#8221;][vc_column_inner column_width_percent=&#8221;100&#8243; gutter_size=&#8221;3&#8243; expand_height=&#8221;yes&#8221; overlay_alpha=&#8221;50&#8243; shift_x=&#8221;0&#8243; shift_y=&#8221;0&#8243; shift_y_down=&#8221;0&#8243; z_index=&#8221;0&#8243; medium_width=&#8221;0&#8243; mobile_width=&#8221;0&#8243; width=&#8221;1\/2&#8243; uncode_shortcode_id=&#8221;106226&#8243; el_class=&#8221;service-box&#8221;][vc_column_text uncode_shortcode_id=&#8221;162781&#8243;]<\/p>\n<p class=\"PDq2pG_selectionAnchorContainer\" style=\"text-align: left;\" data-start=\"2207\" data-end=\"2337\">Whether you already have a sequence or require codon optimization, we supply a fully validated, amplified and <strong>ready-to-use vector<\/strong>.<\/p>\n<p style=\"text-align: left;\" data-start=\"2339\" data-end=\"2441\">Every project undergoes stringent quality-control testing to ensure reliable and reproducible results.<\/p>\n<p>[\/vc_column_text][\/vc_column_inner][vc_column_inner column_width_percent=&#8221;100&#8243; gutter_size=&#8221;3&#8243; expand_height=&#8221;yes&#8221; back_image=&#8221;88246&#8243; overlay_alpha=&#8221;50&#8243; radius=&#8221;xl&#8221; shift_x=&#8221;0&#8243; shift_y=&#8221;0&#8243; shift_y_down=&#8221;0&#8243; z_index=&#8221;0&#8243; medium_width=&#8221;0&#8243; mobile_width=&#8221;0&#8243; width=&#8221;1\/2&#8243; uncode_shortcode_id=&#8221;170276&#8243;][\/vc_column_inner][\/vc_row_inner][\/vc_tab][\/vc_tabs][\/vc_column][\/vc_row][vc_row row_height_percent=&#8221;0&#8243; override_padding=&#8221;yes&#8221; h_padding=&#8221;2&#8243; top_padding=&#8221;3&#8243; bottom_padding=&#8221;0&#8243; back_color=&#8221;accent&#8221; overlay_alpha=&#8221;50&#8243; gutter_size=&#8221;3&#8243; column_width_percent=&#8221;100&#8243; shift_y=&#8221;0&#8243; z_index=&#8221;0&#8243; content_parallax=&#8221;0&#8243; uncode_shortcode_id=&#8221;643961&#8243; back_color_type=&#8221;uncode-palette&#8221; el_id=&#8221;pilot-study-and-small-scale-production&#8221;][vc_column column_width_use_pixel=&#8221;yes&#8221; position_horizontal=&#8221;left&#8221; position_vertical=&#8221;middle&#8221; gutter_size=&#8221;3&#8243; overlay_alpha=&#8221;50&#8243; shift_x=&#8221;0&#8243; shift_y=&#8221;0&#8243; shift_y_down=&#8221;0&#8243; z_index=&#8221;0&#8243; medium_width=&#8221;0&#8243; align_mobile=&#8221;align_center_mobile&#8221; mobile_width=&#8221;0&#8243; width=&#8221;1\/1&#8243; uncode_shortcode_id=&#8221;932974&#8243;][vc_custom_heading text_color=&#8221;color-xsdn&#8221; text_size=&#8221;h1&#8243; text_weight=&#8221;400&#8243; uncode_shortcode_id=&#8221;186375&#8243; text_color_type=&#8221;uncode-palette&#8221;]Pilot study and small-scale production[\/vc_custom_heading][vc_column_text text_color=&#8221;color-109923&#8243; uncode_shortcode_id=&#8221;406171&#8243; text_color_type=&#8221;uncode-palette&#8221;]<strong>Small-scale production enables<\/strong> us to validate expression, optimize conditions and <strong>characterize your protein<\/strong> in terms of purity, identity and biological activity. You receive a detailed report containing clear recommendations.[\/vc_column_text][\/vc_column][\/vc_row][vc_row row_height_percent=&#8221;40&#8243; override_padding=&#8221;yes&#8221; h_padding=&#8221;2&#8243; top_padding=&#8221;2&#8243; bottom_padding=&#8221;4&#8243; back_color=&#8221;accent&#8221; overlay_alpha=&#8221;70&#8243; gutter_size=&#8221;3&#8243; column_width_percent=&#8221;100&#8243; shift_y=&#8221;0&#8243; z_index=&#8221;0&#8243; content_parallax=&#8221;0&#8243; uncode_shortcode_id=&#8221;109795&#8243; back_color_type=&#8221;uncode-palette&#8221;][vc_column column_width_use_pixel=&#8221;yes&#8221; position_horizontal=&#8221;left&#8221; position_vertical=&#8221;middle&#8221; gutter_size=&#8221;3&#8243; overlay_alpha=&#8221;50&#8243; shift_x=&#8221;0&#8243; shift_y=&#8221;0&#8243; shift_y_down=&#8221;0&#8243; z_index=&#8221;0&#8243; medium_width=&#8221;0&#8243; align_mobile=&#8221;align_center_mobile&#8221; mobile_width=&#8221;0&#8243; width=&#8221;1\/1&#8243; uncode_shortcode_id=&#8221;932974&#8243;][vc_row_inner row_inner_height_percent=&#8221;0&#8243; overlay_alpha=&#8221;0&#8243; gutter_size=&#8221;4&#8243; shift_y=&#8221;0&#8243; z_index=&#8221;0&#8243; uncode_shortcode_id=&#8221;139308&#8243;][vc_column_inner column_width_percent=&#8221;100&#8243; gutter_size=&#8221;3&#8243; style=&#8221;dark&#8221; overlay_alpha=&#8221;50&#8243; shift_x=&#8221;0&#8243; shift_y=&#8221;0&#8243; shift_y_down=&#8221;0&#8243; z_index=&#8221;0&#8243; medium_width=&#8221;0&#8243; mobile_width=&#8221;0&#8243; width=&#8221;1\/2&#8243; uncode_shortcode_id=&#8221;524346&#8243;][vc_column_text uncode_shortcode_id=&#8221;203114&#8243;]<\/p>\n<p class=\"PDq2pG_selectionAnchorContainer\" data-start=\"2713\" data-end=\"2762\">The pilot study is a decisive stage. It includes:<\/p>\n<ul data-start=\"2764\" data-end=\"3059\">\n<li data-section-id=\"1ldyros\" data-start=\"2764\" data-end=\"2833\">Small-volume expression, from tens of millilitres in culture flasks<\/li>\n<li data-section-id=\"c3srmc\" data-start=\"2834\" data-end=\"2868\">Recombinant protein purification<\/li>\n<li data-section-id=\"10bzvf2\" data-start=\"2869\" data-end=\"2979\">Comprehensive characterization using SDS-PAGE, Western blotting, protein quantification and activity testing<\/li>\n<li data-section-id=\"14o9wya\" data-start=\"2980\" data-end=\"3059\">Parallel assessment of multiple conditions to identify the optimal parameters<\/li>\n<\/ul>\n<p data-start=\"3061\" data-end=\"3213\">At the end of the proof-of-concept study, you receive a detailed report and a clear go\/no-go recommendation before investing in larger-scale production.<\/p>\n<p>[\/vc_column_text][\/vc_column_inner][vc_column_inner column_width_percent=&#8221;100&#8243; gutter_size=&#8221;3&#8243; override_padding=&#8221;yes&#8221; column_padding=&#8221;1&#8243; overlay_alpha=&#8221;50&#8243; shift_x=&#8221;0&#8243; shift_y=&#8221;0&#8243; shift_y_down=&#8221;0&#8243; z_index=&#8221;0&#8243; medium_width=&#8221;0&#8243; mobile_width=&#8221;0&#8243; width=&#8221;1\/2&#8243; uncode_shortcode_id=&#8221;156710&#8243;][vc_single_image media=&#8221;99905&#8243; media_width_percent=&#8221;100&#8243; media_ratio=&#8221;four-three&#8221; shape=&#8221;img-round&#8221; radius=&#8221;xl&#8221; uncode_shortcode_id=&#8221;263019&#8243;][\/vc_column_inner][\/vc_row_inner][\/vc_column][\/vc_row][vc_row row_height_percent=&#8221;0&#8243; override_padding=&#8221;yes&#8221; h_padding=&#8221;2&#8243; top_padding=&#8221;3&#8243; bottom_padding=&#8221;3&#8243; back_color=&#8221;color-xsdn&#8221; overlay_alpha=&#8221;50&#8243; gutter_size=&#8221;3&#8243; column_width_percent=&#8221;100&#8243; shift_y=&#8221;0&#8243; z_index=&#8221;0&#8243; content_parallax=&#8221;0&#8243; uncode_shortcode_id=&#8221;890170&#8243; back_color_type=&#8221;uncode-palette&#8221; el_id=&#8221;Large-scale-up-production-scaling-up&#8221;][vc_column column_width_use_pixel=&#8221;yes&#8221; position_horizontal=&#8221;left&#8221; position_vertical=&#8221;middle&#8221; gutter_size=&#8221;3&#8243; overlay_alpha=&#8221;50&#8243; shift_x=&#8221;0&#8243; shift_y=&#8221;0&#8243; shift_y_down=&#8221;0&#8243; z_index=&#8221;0&#8243; medium_width=&#8221;0&#8243; align_mobile=&#8221;align_center_mobile&#8221; mobile_width=&#8221;0&#8243; width=&#8221;1\/1&#8243; uncode_shortcode_id=&#8221;932974&#8243;][vc_custom_heading text_color=&#8221;color-109923&#8243; text_size=&#8221;h1&#8243; text_weight=&#8221;400&#8243; uncode_shortcode_id=&#8221;961467&#8243; text_color_type=&#8221;uncode-palette&#8221;]Large scale up production &amp; scaling-up[\/vc_custom_heading][\/vc_column][\/vc_row][vc_row row_height_percent=&#8221;0&#8243; override_padding=&#8221;yes&#8221; h_padding=&#8221;2&#8243; top_padding=&#8221;0&#8243; bottom_padding=&#8221;4&#8243; overlay_alpha=&#8221;50&#8243; gutter_size=&#8221;3&#8243; column_width_percent=&#8221;100&#8243; shift_y=&#8221;0&#8243; z_index=&#8221;0&#8243; content_parallax=&#8221;0&#8243; uncode_shortcode_id=&#8221;877940&#8243;][vc_column column_width_percent=&#8221;100&#8243; position_vertical=&#8221;bottom&#8221; align_horizontal=&#8221;align_center&#8221; gutter_size=&#8221;0&#8243; override_padding=&#8221;yes&#8221; column_padding=&#8221;2&#8243; expand_height=&#8221;yes&#8221; overlay_alpha=&#8221;50&#8243; radius=&#8221;hg&#8221; shift_x=&#8221;0&#8243; shift_y=&#8221;0&#8243; shift_y_down=&#8221;0&#8243; z_index=&#8221;0&#8243; medium_width=&#8221;0&#8243; mobile_width=&#8221;0&#8243; width=&#8221;1\/1&#8243; uncode_shortcode_id=&#8221;204056&#8243; back_color_type=&#8221;uncode-solid&#8221; back_color_solid=&#8221;#ebf6fa&#8221;][vc_row_inner][vc_column_inner column_width_percent=&#8221;100&#8243; gutter_size=&#8221;3&#8243; override_padding=&#8221;yes&#8221; column_padding=&#8221;3&#8243; overlay_alpha=&#8221;50&#8243; shift_x=&#8221;0&#8243; shift_y=&#8221;0&#8243; shift_y_down=&#8221;0&#8243; z_index=&#8221;0&#8243; medium_width=&#8221;0&#8243; mobile_width=&#8221;0&#8243; width=&#8221;1\/1&#8243; uncode_shortcode_id=&#8221;145765&#8243;][vc_column_text text_color=&#8221;color-109923&#8243; uncode_shortcode_id=&#8221;109595&#8243; text_color_type=&#8221;uncode-palette&#8221;]We provide controlled scale-up and large-scale batch production (up to several grams) using optimized processes, high-purity purification and comprehensive characterization. The resulting <strong>proteins are ready for preclinical or clinical applications<\/strong>.[\/vc_column_text][vc_column_text uncode_shortcode_id=&#8221;163221&#8243;]<\/p>\n<p class=\"PDq2pG_selectionAnchorContainer\" data-start=\"3503\" data-end=\"3664\">From pilot production to research-scale batches (up to several hundred milligrams or litres of culture supernatant) we ensure controlled and reproducible scale-up.<\/p>\n<p data-start=\"3666\" data-end=\"3687\">Our services include:<\/p>\n<ul data-start=\"3689\" data-end=\"3873\">\n<li data-section-id=\"17y32o1\" data-start=\"3689\" data-end=\"3777\"><strong>Recombinant protein purification by affinity chromatography<\/strong> or another suitable method<\/li>\n<li data-section-id=\"1th6nux\" data-start=\"3778\" data-end=\"3805\">Tag removal when required<\/li>\n<li data-section-id=\"1fam7mh\" data-start=\"3806\" data-end=\"3821\">Concentration<\/li>\n<li data-section-id=\"1himv77\" data-start=\"3822\" data-end=\"3834\">Aliquoting<\/li>\n<li data-section-id=\"15zeb2n\" data-start=\"3835\" data-end=\"3873\">Comprehensive batch characterization<\/li>\n<\/ul>\n<p data-start=\"3875\" data-end=\"4040\">Every batch is supplied with a complete certificate of analysis and is<strong> ready for applications in immunology,<\/strong> <strong>recombinant protein vaccines<\/strong> or therapeutic development.<\/p>\n<p>[\/vc_column_text][vc_single_image media=&#8221;110922&#8243; 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