Production of hybridoma-derived antibodies
End-to-end hybridoma production. Entrust us with your cell lines (whether frozen or in culture) and our teams will transform your biological material into a purified, ready-to-use antibody batch.
The benefits of the hybridoma system
Customized, monitored antibody production for requirements ranging from milligrams to industrial scale.
Optimize your research and development projects with reliable, fast and fully controlled monoclonal antibody production. At RD-Biotech, we draw on more than 25 years of solid hybridoma expertise to help you achieve your objectives and provide high-performance solutions tailored to your needs.
Our commitment is simple: to supply high-quality, ready-to-use monoclonal antibodies that meet the industry’s most stringent standards. Through a rigorous, optimized production process, we ensure consistency, performance and compliance, enabling you to carry out your projects more efficiently and with complete peace of mind.
In vitro hybridoma production
Optimize your research and development projects with reliable, fast and fully controlled production of hybridoma-derived antibodies. At RD-Biotech, we draw on more than 25 years of solid hybridoma expertise to help you achieve your objectives and provide high-performance solutions tailored to your needs.
Our commitment is simple: to supply high-quality, ready-to-use monoclonal antibodies that meet the industry’s most stringent standards. Through a rigorous, optimized production process, we ensure consistency, performance and compliance, enabling you to carry out your projects more efficiently and with complete peace of mind.
Monoclonal antibody sequencing
Safeguard your clones and ensure their long-term availability through high-precision sequencing, converting your hybridomas into genetic sequences ready for engineering and recombinant production.
Converting a hybridoma into a digital format is a strategic step that protects your intellectual property and opens the way to future technologies. RD-Biotech supports this transition through its antibody-sequencing expertise.
Clone Preservation and Security
Variable-region sequencing—VH and VL—can be offered from the earliest stages of the development or production process.
- Protection against loss: anticipate the risks associated with genetic drift, declining productivity or cryopreservation incidents.
- A permanent digital asset: converting your physical clone into genetic data ensures the long-term preservation of your antibody.
Transition to Recombinant Development
Sequencing is the cornerstone of modern antibody engineering.
Once the sequence has been established, RD-Biotech can help you transition to recombinant bioproduction:
- Complete reproducibility: production in mammalian expression systems such as CHO and HEK cells ensures consistent batch-to-batch quality.
- Optimization: options include humanization, isotype switching and antibody-format modification, such as scFv or Fab.
- Freedom of production: production no longer depends on the viability of a hybridoma cell line, but on a stable, optimized sequence.
Cell bank storage
To safeguard your clones of interest, we offer cell bank production and vial storage services in liquid nitrogen tanks.
Cell banks produced at RD-Biotech undergo comprehensive quality-control testing:
- Confirmation of the absence of mycoplasma contamination
- Confirmation of the absence of bacterial and fungal contamination
- Post-freezing testing to assess cell viability, cell growth and productivity
Our storage service is highly secure, with continuous temperature monitoring 24 hours a day, seven days a week, and restricted, secure access.
We also offer mirrored storage across multiple sites to protect your material against any major incident.
Entrusting your clones to our experts ensures that your monoclonal antibodies remain available for future production whenever you need them.
